13 Bioreactor Manufacturers in 2024
This section provides an overview for bioreactors as well as their applications and principles. Also, please take a look at the list of 13 bioreactor manufacturers and their company rankings. Here are the top-ranked bioreactor companies as of April, 2024: 1.Corning Incorporated, 2.Beckman Coulter, Inc., 3.bbi-biotech GmbH.
Table of Contents
What Is a Bioreactor?
Bioreactors are devices that utilize biological processes mediated by enzymes, cells, and microorganisms to produce and analyze substances. Unlike chemical reactions, biological reactions in bioreactors tend to be slower but are advantageous for producing fewer byproducts and maintaining catalytic activity without the need for high temperatures and pressures. This makes bioreactors cost-effective and essential for various applications, including cell culture.
Uses of Bioreactors
Bioreactors find applications in numerous industries, such as:
- Food Production: Used to produce fermented products like miso, soy sauce, sake, and wine.
- The Chemical Industry: Mass production of amino acids and sugars.
- Medicine and Research: Producing functional substances through cell culture.
- Physicochemical Analysis: Utilizing biosensors and autoanalyzers for detecting and quantifying substances.
Principles of Bioreactors
Bioreactors operate by managing conditions such as temperature, pH, and pressure to facilitate reactions with immobilized enzymes and other biological elements, leading to the synthesis, decomposition, or conversion of materials to obtain desired products. Cells, microorganisms, and purified enzymes serve as primary reaction elements, with immobilization techniques enhancing separation efficiency from the products.
Types of Bioreactors
Variants of bioreactors include:
- Liquid bioreactors for processes involving liquid raw materials.
- Solid bioreactors, used in industries like koji making and enzyme production.
- Photosynthetic bioreactors for utilizing plant cells, algae, and photosynthetic bacteria.
- Microbioreactors for analytical applications, designed for small volume analyses.
Other Information About Bioreactors
Reaction Field Conditions
The aeration, mixing, and temperature control in bioreactors vary greatly depending on the state of the reaction materials and the type of organisms involved. Methods include aeration and agitation for aerobic organisms and specific nutrient and light supply for photosynthetic organisms. Microbioreactors, used for analysis, require precise control of temperature and volume to ensure accuracy.
Synthesis of Optically Active Compounds in Bioreactors
Bioreactors excel in synthesizing optically active compounds, offering advantages like room temperature operation, normal pressure, neutral pH, selectivity, fewer byproducts, and higher yields.
Applications of Bioreactors in Regenerative Medicine
Bioreactors are pivotal in regenerative medicine for cultivating large quantities of cells, such as iPS cells, using techniques like 3D floating cultures and specially designed agitation mechanisms to enhance culture efficiency with minimal stress on the cells.
List of 13 Bioreactor Manufacturers
*Including some distributors, etc.
Sort by Features
- Default
- Company Size: largest first
- Year Founded: oldest first
- Year Founded: earliest first
Sort by Area
- United States of America
- China
- Germany
- Japan
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Corning Incorporated
Bioreactor
Manufacturer Overview
Corning Incorporated, founded in 1851 and headquartered in Corning, New York, is a manufacturer and supplier of specialty glass, ceramics, and optical fiber. Their offerings include optical fiber for long-distance light signal transmission, specialty glass for applications like displays and lighting, ceramics for various uses, such as cookware and medical implants, and advanced materials like 3D printing powders and ceramic matrix composites. Additionally, Corning provides products for the life sciences industry, such as labware, consumables, and analytical instruments.
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Beckman Coulter, Inc.
Bioreactor
Manufacturer Overview
Beckman Coulter, Inc. is a manufacturer of scientific research instruments primarily for the academia and pharmaceutical markets. The company is a merger between Beckman Instruments, Inc. and Coulter Corporation based in Indiana, United States with a history dating back to 1935. Beckman Coulter develops and manufactures instruments for the clinical research market, and applied markets including food and beverages, agriculture, oil and gas, and aerospace. The company's range of instrument and reagents include Air and Liquid Particle Counters, Centrifuges, and Genomic Solutions.
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American Alloy Fabricators Inc.
Bioreactors
Manufacturer Overview
American Alloy Fabricators, founded in 1989, is a manufacturer of ASME-certified custom equipment such as pressure vessels, reactors, pressure filters, storage tanks, and pipping equipment such as elbows and tee fittings with gaskets used in the biotechnology, pharmaceutical, food processing, cosmetics, and nutraceuticals industries. The Norristown, Pennsylvania-based company provides custom alloy fabrication metal services, welding, and alloy fabrication finishes such as polishing using materials like stainless steel, Hastelloy, Inconel, Monel, and alloy 20.
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Augusta Fiberglass
Bioreactors
Manufacturer Overview
Augusta Fiberglass, since 1974, is a manufacturer of custom-designed fabricated fiberglass and reinforced plastic products such as tanks, pipes & ducts, hoods, stacks & stack liners, and scrubbers used in chemical, food & beverage, mining, industrial and pharmaceutical industries. Located in Blackville,SC, the company offers field services such as emergency repair & maintenance, erection of vessels, inspection & modifications, fabrications and site surveys by equipped and RTP-1-certified workers. The company has an ASME RTP certificate and hence can stamp vessels with the RTP mark.
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Lee Industries, Inc.
Bioreactors
Manufacturer Overview
Lee Industries, Inc. is a custom processing solutions manufacturer based in Philipsburg, Pennsylvania. Founded in 1927, the company's product lineup includes vacuum evaporators for concentration and crystallization, ribbon and paddle blenders for integrating dry powders or granular mixtures, and agitators for dispersion and homogenization of product formulations. The company also offers engineering and fabrication as well as lab and pilot plant testing of custom units. Lee Industries, Inc. serves various industries, with client corporations like Procter & Gamble, Zoetis, and the Campbell Soup Company.
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Glen Mills, Inc.
Bioreactors
Manufacturer Overview
Glen Mill Inc. was founded in 1980 and headquartered in Clifton, New Jersey. The company is a provider of grinding and comminution equipment that reduces particle size for laboratory professionals, researchers, and engineers based around the world. The company blends and samples grinding media of all types. The company’s product list includes 3D inversion powder mixers, dry and wet milling equipment, cell disruption equipment, and sieving equipment. The company also offers rental options and grinding and tolling services for customers.
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Paul Mueller Company
Bioreactors
Manufacturer Overview
Paul Mueller Company, established in 1940, is an American manufacturer of stainless steel processing systems and equipment, headquartered in Springfield, Missouri. The company's product range includes various types of tanks for storage, processing, and serving. Additionally, Paul Mueller Company offers diverse processing systems for applications such as beverage infusion, heat recovery, and refrigeration. Furthermore, the company's PyroPure line features pure steam generators and condensing units designed for producing water-for-injection (WFI) quality pure steam and WFI quality distillate. Paul Mueller Company serves various industries including food, beverage, brewing, and wine, chemical, dairy farming and processing, oil and gas, as well as pharmaceuticals.
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Hydro Engineering, Inc.
Bioreactors
Manufacturer Overview
Hydro Engineering, Inc., founded in 1980, is a manufacturer of Hydroblaster, Hydrokleen, and Hydropad products for washing, collecting, and recycling wash water. The products are used in recycling and filtration equipment, pressure washers, and above-ground steel portable/permanent wash racks. Based in Salt Lake City, UT, the company serves car washes, construction, military, and manufacturing industries. The CE, UL, and CSA standards are applied to the products produced as the company is ISO 9001:2015 Certified. The company offers diagnostics, safety system testing, pump rebuilding, and heating system repair services for pressure washers.
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GPC Bio
Bioreactor
Manufacturer Overview
GPC Bio is a bioreactor, fermenter, and processing equipment manufacturer, established in 2008 and based in Perigny, France, and Newark, USA. It manufactures benchtop bioreactors, single-use bioreactors, and photo bioreactors. It also provides bioreactor fermenters and turnkey solutions, which are greater in scale than the aforementioned products. The products are targeted at vaccine manufacturers, the food industry, veterinary, biopharmaceutical companies, and many more. It applies a quality standard of GAMP V5 (Good Automated Manufacturing Practice).
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bbi-biotech GmbH
Bioreactor
Company Overview
bbi-biotech GmbH is a bioreactor as well as fermenter manufacturer and distributor, established in 2009 and headquartered in Berlin, Germany. The company's range of products includes compact bioreactor/fermentor with extensive equipment capabilities, bioreactors and fermentors featuring two cultivation vessels, and multi-bioreactors capable of accommodating up to 12 parallel vessels. It also offers in-situ sterilizable photobioreactors, in-situ sterilizable airlift photobioreactors, and photobioreactors designed for microalgae cultivation in laboratory settings, catering to the biotechnology, pharmaceutical, cosmetic, and food industries. The company also collaborates with Abitep GmbH, B&R, Cercell, Gemtec, IGV Biotech, and InVivo Biotech Services GmbH in the research and development process.
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Solida Biotech
Bioreactor
Company Overview
Solida Biotech is a bioreactor as well as fermenter manufacturer and distributor, established in 2001 and headquartered in Munchen, Germany. It manufactures laboratory bioreactors like compact bioreactors, advanced modular bioreactors, and single-use bioreactors as well as pilot and industrial bioreactors such as SIP/CIP Pilot 20-500L Bioreactors and Fermenters and SIP/CIP Industrial 500I-30m3 Bioreactors. It also produces multi-assay analyzers, gas analyzers, online biomass sensors, automation and controllers, and Bioflex software & SCADA. The fields of applications are antibiotics, biomass, vaccines, proteins, and many others. All of Solida Biotech’s bioprocess equipment meets the latest GLP, cGMP, GAMP, FDA, and SFDA standards.
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Kindle Tech
High Pressure Reactor
Distributor Overview
Kindle Tech is a professional laboratory equipment supplier that was founded in 2015 and is headquartered in Zhengzhou, China. Its main activity is the supply of laboratory equipment, including analytical instruments, equipment for microbiology, and equipment for environmental analysis. The company also offers a wide range of services, such as installation, calibration, and maintenance. Kindle Tech's products are used by a wide range of customers, including academic institutions, pharmaceutical companies, and environmental testing laboratories. The organization, through its specialized teamwork and rich experienced engineers, provide custom made service and equipment, custom tailoring hardware and software equipment requirements to worldwide customers.
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Bioreactor Manufacturer Ranking
*Including some distributors, etc.Ranking as of April 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | Corning Incorporated |
16.1%
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| 2 | Beckman Coulter, Inc. |
12.5%
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| 3 | bbi-biotech GmbH |
12.2%
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| 4 | Solida Biotech |
9.0%
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| 5 | American Alloy Fabricators Inc. |
8.6%
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| 6 | Paul Mueller Company |
7.5%
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| 7 | Hydro Engineering, Inc. |
7.2%
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| 8 | Lee Industries, Inc. |
6.5%
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| 9 | GPC Bio |
5.7%
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| 10 | Augusta Fiberglass |
5.7%
|
Derivation Method
The ranking is calculated based on the click share within the bioreactor page as of April 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
- Satake Martimics Co., Ltd.: 200
Newly Established Company
- American Alloy Fabricators Inc.: 1989 (35 years ago)
- Paul Mueller Company: 1940 (84 years ago)
- Beckman Coulter, Inc.: 1935 (89 years ago)
Company with a History
- Corning Incorporated: 1851 (173 years ago)
- Satake Martimics Co., Ltd.: 1920 (104 years ago)
- Beckman Coulter, Inc.: 1935 (89 years ago)
Bioreactor Manufacturers in United States
*Including some distributors, etc.
- Corning Incorporated
- Beckman Coulter, Inc.
- American Alloy Fabricators Inc.
- Augusta Fiberglass
- Lee Industries, Inc.
- Glen Mills, Inc.
- Paul Mueller Company
- Hydro Engineering, Inc.
Global Distribution of Bioreactor Manufacturers by Country
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
United States of America
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8 | 66.7% |
Germany
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2 | 16.7% |
Japan
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1 | 8.3% |
China
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1 | 8.3% |
List of Bioreactor Products
13 products are listed.
Satake Martimics Co., Ltd.
VMF REACTOR/SPG SPG Fillary Sparse Collaboration Versus Reactor®
■ Dedicated aircraft development / customization support, single use support according to the requirement specifications VERSUS REACTOR is a new an...
Satake Martimics Co., Ltd.
Single use biororia staff with weight management for production for commercial commercial production Purfusion system VMF-WSUB REACTOR
■ Dedicated aircraft development / customization compatible ・ Single use exclusively according to the required specifications When using iPS cells...
Satake Martimics Co., Ltd.
Commercial production single use system SINGLEUSE BIO REACTOR
■ Dedicated aircraft development / customization support, single use support according to the requirement specifications The VMF50L/200L-SUB is a s...
Satake Martimics Co., Ltd.
High -efficiency turbine HS100 / high -discharge axis wing HR100 High -performance viola staff HSF REACTOR
20+ people viewing
■ High -efficiency turbine ・ In -tank coil heat transmission specification ・ Actual machine scale up The target cells and bacteria, such as relat...
Beckman Coulter Life Sciences
Microbiolector XT designed based on highly reliable Biolector Pro technology
By using a high -looped microbiolet cult, you can evaluate the main culture parameters of ebeated bacteria and anaerobic bacteria, such as the numb...
Envyro Vision Co., Ltd.
Limited bio technology by bio circle reduced industrial waste cost microorganism decomposition parts Cleaning table bio circle
Microbial decomposition and cleaning by biocircle liquids manufactured with natural materials and ingredients that do not produce waste in consider...
