16 Tetrahydrofuran Manufacturers in 2024
This section provides an overview for tetrahydrofuran as well as their applications and principles. Also, please take a look at the list of 16 tetrahydrofuran manufacturers and their company rankings. Here are the top-ranked tetrahydrofuran companies as of April, 2024: 1.Ashland, 2.MilliporeSigma, 3.Hefei TNJ Chemical Industry Co.,Ltd..
Table of Contents
What Is Tetrahydrofuran?
Tetrahydrofuran is a type of saturated five-membered heterocyclic compound with one oxygen atom in the ring.
It is also known as THF or oxolane. About 200,000 tons are produced annually, and the most widely used industrial production method is the acid-catalyzed dehydration of 1,4-butanediol.
Using the coordination properties of oxygen, it can be used as a ligand for Lewis acids and metal ions. Solutions such as BH3-THF, a stable complex with borane, are commercially available.
Due to its low flash point of -14.5°C, it is designated as a hazardous substance.
Uses of Tetrahydrofuran
- Solvent for synthetic resins such as polyvinyl chloride resin and organic synthetic reaction solvents
- Solvent for coating synthetic leather, etc.
- Solvent for vinyl and epoxy adhesives
- Solvent for printing inks
- Solvents for special resins such as photosensitive resins
As shown above, they are widely used as solvents. It can also be used as a solvent for reactions such as the Grignard reaction and the Wittig reaction and as a reaction and purification solvent in the manufacture of pharmaceuticals and agricultural chemicals.
Tetrahydrofuran is also used as a synthetic raw material for nylon, polyethers, and polytetramethylene ether glycol. It is also used as an extractant in the petrochemical industry and as a heat-shrinkable film and moisture-proofing agent for vinyl chloride resin.
Properties of Tetrahydrofuran
Tetrahydrofuran is a colorless liquid with a distinctive aroma similar to ether. It is well soluble in many organic solvents and water. Tetrahydrofuran has a density of 0.8892 g/mL at 20°C, a melting point of -108.4°C, and a boiling point of 66°C.
Tetrahydrofuran can also be converted to γ-butyrolactone by oxidation. Tetrahydrofuran is also a cyclic ether containing one oxygen in a saturated five-membered ring. Tetrahydrofuran's chemical formula is C4H8O and its molecular weight is 72.11.
Other Information on Tetrahydrofuran
1. Tetrahydrofuran Synthesis
Tetrahydrofuran is produced by the hydrogenation of 1,4-butindiol, which is obtained by the condensation of formaldehyde and acetylene.
Tetrahydrofuran can also be obtained by contact reduction of furan or maleic anhydride.
Tetrahydrofuran can also be obtained by oxidation of n-butane to maleic anhydride, followed by hydrogenation.
2. Formation of Peroxide by Tetrahydrofuran
When tetrahydrofuran comes in contact with air for a long time, it generates explosive peroxides. Evaporation and solidification of tetrahydrofuran that has been stored for a long time is particularly dangerous. To prevent oxidation of tetrahydrofuran, small amounts of p-cresol or hydroquinone are added to commercial products.
3. Ring-Opening Polymerization of Tetrahydrofuran
Ring-opening polymerization of tetrahydrofuran yields the polyether polytetramethylene ether glycol. Poly tetramethylene ether glycol is also called PTMG, PTMEG, polyoxy tetramethylene glycol, or poly tetrahydrofuran. Polytetrahydrofuran is also known as polytetrahydrofuran.
The molecular weight of a typical polytetramethylene ether glycol product is between 1,000 and 2,000. It is used as a raw material for polyurethanes, such as the elastic fiber Spandex and thermoplastic elastomers.
List of 16 Tetrahydrofuran Manufacturers
*Including some distributors, etc.
Sort by Features
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- Company Size: largest first
- Year Founded: oldest first
- Year Founded: earliest first
Sort by Area
- China
- India
- Japan
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SANKYO CHEMICAL CO.,LTD.
THF
Manufacturer Overview
Sankyo Chemical Co. LTD., established in 1957 and headquartered in Nagoya, Japan, is a manufacturer of several intermediate materials, including paints, industrial cleaning agents, thinners, organic industrial chemicals, and adhesives. The products can be used in several areas, including silk screen printing, wiping off resin, washing agents for flux, metal processing, and mold forming. The company accepts contract manufacturing and provides several environmentally friendly products that comply with ISO 14001, the Industrial Safety and Health Law, and the PRTR (Pollutant Release and Transfer Register) Law.
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Junsei Chemical Co.,Ltd.
Tetrahydrofuran
Manufacturer Overview
Junsei Chemical Co. Ltd., established in 1948 and headquartered in Tokyo, Japan, is a manufacturer of chemical reagents and chemical products, including commissioned synthesis of chemical products. Some of the products it makes include Sodium chloride solution, concentrated glycerin, calcium chloride, ascorbic acid, and nitric acid. The chemical products have a wide range of applications and can be used in pathological examination, as food additives, for analysis, and in the pharmaceutical industry. All its plants, including its research institute, are ISO4001 and ISO9001 certified, while its Saitama and Ibaraki plants are equipped with buildings that comply with GMP.
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Mitsubishi Chemical Corporation
Tetrahydrofuran
Manufacturer Overview
Mitsubishi Chemical Corporation was founded in 1933 and has a head office in Tokyo, Japan. Mitsubishi Chemical Corporation provides products including chemicals, industrial gases, and health care products to customers globally. Mitsubishi Chemical Group’s performance products division manufactures and distributes. functional food materials, electronic and electrical components, specialty chemicals, and other products. Mitsubishi Chemical health care products include pharmaceuticals, drug discovery solutions, diagnostic reagents, and instruments for medical use. Mitsubishi Chemical Corporation also provides other services such as engineering, information systems, logistics, and consulting.
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RIDHDHI SIDHDHI CHEMICALS
Tetrahydrofuran
Manufacturer Overview
RIDHDHI SIDHDHI CHEMICALS was established in 2011, and its headquarters is in Gujarat, India, as a manufacturer of pure quality chemicals such as benzene, acetone, butyl acetate, toluene, dimethyl formamide, methylene dichloride, IPA, and xylene. The items are fabricated by proficient and knowledgeable production professionals with extensive skills in the corresponding fields of interest. The organization maintains a competitive price tactic to accommodate its consumers' budgetary requirements. It consistently prioritizes client satisfaction by diligently endeavouring to deliver chemical goods of outstanding quality.
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REE ATHARVA LIFESCIENCE PVT. LTD.
Tetrahydrofuran
Manufacturer Overview
Ree Atharva Lifescience Pvt Ltd, founded in 2007, is a manufacturer, supplier, and exporter of solvents and chemicals based in Gujarat, India. The solvents and co-solvents products include petroleum solvents, fine solvents, industrial solvents, ink co-solvents, and reducer co-solvents whereas the chemical products are industrial chemicals, perfume chemicals, lamination chemicals, agrochemicals, and textile chemicals. The company deals with paint thinners, resin adhesives, paint removers, and ink reducers. The products used in pharmaceuticals, agro-industries, ink manufacturing, paint industries, and rubber industries.
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Hefei TNJ Chemical Industry Co.,Ltd.
Tetrahydrofuran
Manufacturer Overview
Hefei TNJ Chemical Industry Co., Ltd, established in 2001, is headquartered in China. The company is a chemical manufacturer and supplier of chemicals to domestic Chinese and global consumers in four primary markets: chemicals, food, pharmaceuticals, and personal care. Chemicals include fine chemicals, agrochemicals, and other chemicals. Food includes agrochemicals, vitamins, amino acids, and food ingredients. Pharmaceuticals include specific chemicals such as Povidone iodine, Clotrimazole crystalline, and Lincomycin. The company also features a CAS databank for CAS-registered chemical compounds.
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MilliporeSigma
Tetrahydrofuran
Manufacturer Overview
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
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Standard Reagents Pvt. Ltd.
Tetrahydrofuran
Manufacturer Overview
Standard Reagents Pvt. Ltd., founded in 2000, is an Indian chemical manufacturer based in Hyderabad, Telangana. The company offers a wide range of chemicals, encompassing analytical reagents (AR) grade and laboratory reagent (LR) grade chemicals, excipients, gas chromatography (GC) solvents, high-performance liquid chromatography (HPLC) and spectroscopy grade solvents, as well as HPLC gradient solvents. Additional offerings include buffer salts, dry solvents, high-purity acids, HPLC grade acids, and ion-pair reagents. Karl-Fischer reagents (KFR) (pyridine-free single solution) and liquid chromatography (LC) with mass spectrometry (MS) are also available. These chemical products find applications in various industries, such as cosmetics, environment, food, biopharmaceuticals, and pharmaceuticals.
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Shandong Hosea Chemical Co., Ltd.
Tetrahydrofuran
Manufacturer Overview
Shandong Hosea Chemical Co., Ltd., established in 1998, based in Weifang City, Shandong Province, China, is a manufacturer of fine chemicals. The company manufactures and researches cellulose ether, chlorine, hydroxide, nitrate and high end chemicals. Industries served include food, textile printing and dyeing, ceramics, paper making, and building materials, among others. The company is one of the Highest 10 Enterprises in Weifang City. Products are sold to several dozens of countries and regions in North and South America, Europe, Asia, Australia and South Africa. Customer service provided include engagement in chemical management, production, R&D and trade.
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Ashland
Tetrahydrofuran
Manufacturer Overview
Ashland, established in 1924, is headquartered in Wilmington, Delaware, and operates as a global manufacturer and supplier of specialty chemicals and ingredients. The company offers tailored solutions catering to multiple sectors such as personal care, pharmaceuticals, construction, and food and beverages. With a specialization in applied chemistry, the company employs an environmental, social, and governance (ESG) framework to promote sustainability. Its products range from specialty additives and functional ingredients designed for enhancing cosmetics to architectural coatings.
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nacalai
Tetrahydrofuran
Company Overview
Nacalai Tesque Inc., founded in 1846 and headquartered in Kyoto, Japan, is a manufacturer of research chemicals, fine chemicals, diagnostics, and the related instruments. Some of its products include cytokines, nucleic acid electrophoresis, cell dissociation reagents, and sialic acid-related products, and it also offers custom and bulk service for bulk reagents and cell culture media. The company has more than 50 domestic distributors and several worldwide, including Asia, the Middle East, Oceania, Europe, and Africa. It is ISO 9001 and ISO 9002 certified, while the Kyoto South brand and Tesque factory are ISO 14001 certified.
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Welinks Group
Tetrahydrofuran
Company Overview
Welinks Group (Zhangjiagang) Co. Ltd, a holding subsidiary of LTH group, established in 2015 and located in Xuyong City, Sichuan Province, China is a manufacturer and supplier of intermediates and chemicals for industrial use. The company’s product portfolio includes N-pentane, 1.4 Butanediol, Tetrahydrofuran (THF), N-Vinyl Pyrrolidone (NVP), and Toluene Diisocyanate (TDI). The products are used for various applications and solutions in various industries including oil exploitation, space flight, medical, automobile, and textile industries.
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Central Drug House
Tetrahydrofuran
Company Overview
Founded in 1981, Central Drug House Ltd. serves the scientific community via manufacturing and marketing a library of over 9,000 products to laboratory fine chemicals and dehydrated culture media with emphasis on purity and service. Examples are acids & bases, adsorbents, disinfectants, indicator papers, oils, and solvents. CDH provides bio chemicals, research chemicals, laboratory reagents, various solvents, stains & indicators, and dehydrated culture media. CDH is ISO 9001 certified and CDHs’ products are in compliance with specifications of IP, BP, USP, and EP standards.
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Zhengzhou Meiya Chemical Products Co.,Ltd.
Tetrahydrofuran
Distributor Overview
Zhengzhou Meiya Chemical Products Co., LTD was founded in 2005 in Henan, China, and is headquartered in Zhengzhou, China. The company is a distributor and exporter of chemicals from China to Europe, Asia, and the Americas. The ISO 9001-certified company specializes in VOC-exempt solvents, paints and coatings, adhesives, PU, and resin for industries such as agriculture, pharmaceuticals, feed, water treatment, and oil field chemicals. The company’s product categories include plant extracts, cosmetics, PU, and resin.
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Otto Chemie Pvt. Ltd
Tetrahydrofuran
Distributor Overview
Founded in Mumbai, India in 2006, Otto Chemie Pvt. Ltd. is an ISO 9001:2015 & GMP certified chemical manufacturing company and distributor. Otto Chemie serves customers in many industries including agriculture and food processing, pharmaceuticals, oil & gas, cement, as well as educational and R&D industries. Product offerings include antibiotics, amino acids, vitamins, detergents, ionic liquids, materials science compounds, labware, oil, metal & ceramic science compounds and tools, oils, reagents, solvents.
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Henan GP Chemicals Co.,Ltd
Tetrahydrofuran
Distributor Overview
Henan GP Chemicals Co., Ltd., established in 2014 with its head office in Zhengzhou and a secondary office in Henan, China, is a distributor of chemical products from China. The company offers over 1,000 products, including chlorinated paraffin, isobutyl isobutyrate, and trioctyl trimellitate. Henan GP Chemicals Co., Ltd.'s main products are used in solvents, plastics and rubber, adhesives, pharmaceuticals, and agriculture. The company also provides custom services that include business-to-business distribution solutions for industrial and specialty chemicals around the world.
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Tetrahydrofuran Manufacturer Ranking
*Including some distributors, etc.Ranking as of April 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | MilliporeSigma |
22.2%
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| 2 | Ashland |
16.7%
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| 3 | Hefei TNJ Chemical Industry Co.,Ltd. |
11.1%
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| 4 | Standard Reagents Pvt. Ltd. |
11.1%
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| 5 | RIDHDHI SIDHDHI CHEMICALS |
5.6%
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| 6 | REE ATHARVA LIFESCIENCE PVT. LTD. |
5.6%
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| 7 | Welinks Group |
5.6%
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| 8 | Central Drug House |
5.6%
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| 9 | Otto Chemie Pvt. Ltd |
5.6%
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| 10 | SANKYO CHEMICAL CO.,LTD. |
5.6%
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Derivation Method
The ranking is calculated based on the click share within the tetrahydrofuran page as of April 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
- Mitsubishi Chemical Corporation: 42,127
- Hefei TNJ Chemical Industry Co.,Ltd.: 210
- Junsei Chemical Co.,Ltd.: 171
Newly Established Company
- REE ATHARVA LIFESCIENCE PVT. LTD.: 2007 (17 years ago)
- Zhengzhou Meiya Chemical Products Co.,Ltd.: 2005 (19 years ago)
- Hefei TNJ Chemical Industry Co.,Ltd.: 2001 (23 years ago)
Company with a History
- Mitsubishi Chemical Corporation: 1933 (91 years ago)
- nacalai: 1934 (90 years ago)
- Junsei Chemical Co.,Ltd.: 1948 (76 years ago)
Global Distribution of Tetrahydrofuran Manufacturers by Country
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
Japan
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4 | 36.4% |
India
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4 | 36.4% |
China
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3 | 27.3% |
