11 Bacitracin Manufacturers in 2024
This section provides an overview for bacitracin as well as their applications and principles. Also, please take a look at the list of 11 bacitracin manufacturers and their company rankings. Here are the top-ranked bacitracin companies as of April, 2024: 1.MedChemExpress, 2.MilliporeSigma, 3.Merck.
Table of Contents
What Is Bacitracin?
Bacitracin, an antibiotic, comprises a mixture of cyclic polypeptides. It originates from the Tracy strain of Bacillus subtilis, commonly found in soil and the human digestive system. The "Tracy strain" designation stems from its initial isolation from a leg wound of a girl named Margaret Tracy. Bacitracin's principal component is bacitracin A.
Uses of Bacitracin
This antibiotic showcases potent antibacterial properties, predominantly against Gram-positive bacteria. It acts bactericidally by obstructing bacterial cell wall formation and cleaving DNA oxidatively. Due to its short action duration, topical application is required multiple times daily. Although bacitracin is nephrotoxic via intramuscular routes, potentially leading to renal failure, and is highly toxic orally, it is formulated into troches and ointments for safe topical wound application.
1. Lozenges
Bacitracin lozenges treat stomatitis from Gram-positive bacteria like Staphylococcus and Streptococcus, preventing bacterial growth in the mouth, reducing inflammation, and alleviating pain. They are also used to ward off secondary infections after tooth extractions and oral surgeries.
2. Ointment
Barramycin, an antibiotic ointment, combines bacitracin and fradiomycin sulfate. Fradiomycin inhibits bacterial protein synthesis. Their synergistic effect makes it a highly effective bactericidal and anti-inflammatory agent for treating purulent skin conditions, wounds, and burns. Being a topical medication, it rarely causes side effects, though kidney issues, hearing loss, and hypersensitivity reactions like rash and itching may occur.
Properties of Bacitracin
Focusing on bacitracin A, its chemical formula is C66H103N17O16S, with a molecular weight of 1,422.71. Its CAS number is 1405-87-4, and it's listed in the Chemical Substances Control Law Official Gazette under publication number 8-474. Bacitracin, a white powder solid at ambient temperatures, melts between 221-225°C. It dissolves easily in water, is soluble in ethanol, and is almost insoluble in ether.
Other Information about Bacitracin
1. Manufacturing Method of Bacitracin
Produced by strains of Bacillus subtilis and Bacillus licheniformis, bacitracin synthesis employs specific bacterial cultures.
2. Precautions for Handling and Storage
Handling Precautions
Incompatible with strong oxidizing agents, handle bacitracin cautiously to avoid contact. Always wear protective gloves, safety goggles with side shields, and long-sleeved protective clothing, and use local exhaust ventilation systems during handling.
Fire Response
In the event of a fire, use water spray, alcohol-resistant foam, dry powder, carbon dioxide, or sand to extinguish, as combustion may release toxic gases such as carbon monoxide (CO), carbon dioxide (CO2), nitrogen oxides (NOx), and sulfur oxides (SOx).
Eye Contact
If bacitracin contacts the eyes, rinse thoroughly with water to prevent damage and seek medical attention promptly.
Inhalation Response
If inhaled, move to an area with fresh air immediately. Provide artificial respiration if breathing has stopped, and consult a doctor if symptoms persist.
Storage Guidelines
Store bacitracin in a tightly sealed glass container within a refrigerator (2-10℃), away from direct sunlight, in a locked storage area.
List of 11 Bacitracin Manufacturers
*Including some distributors, etc.
Sort by Features
- Default
- Company Size: largest first
- Year Founded: oldest first
- Year Founded: earliest first
Sort by Area
- United States of America
- Denmark
- India
- Japan
- United Kingdom
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MedChemExpress
Bacitracin
Manufacturer Overview
MedChemExpress (MCE), is headquartered in Monmouth Junction, New Jersey, and is a supplier of research chemicals and biochemicals for laboratory and scientific use. The company’s product range includes biochemical assay reagents, isotope-labeled compounds, inhibitory antibodies, recombinant proteins, and fluorescent dyes. These products are used in various biopharmaceutical research and development fields, including areas such as infection, cardiovascular diseases, neurodegenerative diseases, diabetes, and autoimmune diseases. The company is ISO 19001 certified and provides testing services within the ISO 17025 framework, offering bulk and custom product services and support for metrological traceability.
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Santa Cruz Biotechnology, Inc.
Bacitracin
Company Overview
Santa Cruz Biotechnology, Inc., established in 1991 and headquartered in Dallas, Texas, is an American manufacturer and supplier specializing in biological products for medical research. Initially providing antibodies to the research community, they expanded their offerings to include gene silencers like siRNA and shRNA (plasmid and lentiviral), targeting all known mouse and human genes. Over time, Santa Cruz Biotechnology provides over 175,000 research biochemicals under the brand ChemCruz, including protein-interacting inhibitors, substrates, and activators, tailored for studying protein functions. The company offers monoclonal primary antibodies, designed for various mammalian and non-mammalian protein targets, along with corresponding binding secondary antibodies.
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KANTO CHEMICAL CO.,INC.
Bacitracin
Manufacturer Overview
Kanto Chemical Co. Inc., founded in 1944 and headquartered in Tokyo, Japan, is a reagent manufacturer with overseas affiliates in other countries, including China, France, USA, Taiwan, and Malaysia. Its product portfolio includes analytical reagents, ionic liquids, Iodine compounds, ultra-pure chemicals, and water analysis kits. The company is also developing regenerative medicine and genetics reagents and has over 50,000 products. It has several certifications, including ISO 9001, acquired in 1994, making it the first Japanese company in the reagent industry. Other certifications are ISO 14001, ISO 13485, and ISO/IEC 17025.
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Merck
Bacitracin
Manufacturer Overview
Merck, started in 1668 and based in Darmstadt, Germany, is a supplier of solutions and services for research, development, and manufacture of pharmaceutical and biotechnological drug therapies. The company serves the life science industry and has a broad portfolio of 300,000 products, including biopharmaceutical manufacturing, industrial microbiology, reagent, life science research, and water purification products. It is available in 66 countries, brings together six brands, and has several ISO certifications, including ISO 13485, ISO 14001, ISO 13485, and ISO 50001.
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MilliporeSigma
Bacitracin
Manufacturer Overview
Millipore Sigma, formerly known as Sigma-Aldrich, was created in 175 through the merger of Sigma Chemical Company and Aldrich Chemical company and today is a subsidiary of Merck. Millipore Sigma is a life science and biotechnology company serving the industry with several products and services. Some of their product categories include peptide synthesis materials, biochemicals, building blocks, catalysts, chemical biology, chemical synthesis, flavors & fragrances, formulation, lab chemicals, lab safety, APIs, and stable isotopes. Services include characterization, contract manufacturing, custom products, software, support, testing, and mRNA development & manufacturing.
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nacalai
Bacitracin
Company Overview
Nacalai Tesque Inc., founded in 1846 and headquartered in Kyoto, Japan, is a manufacturer of research chemicals, fine chemicals, diagnostics, and the related instruments. Some of its products include cytokines, nucleic acid electrophoresis, cell dissociation reagents, and sialic acid-related products, and it also offers custom and bulk service for bulk reagents and cell culture media. The company has more than 50 domestic distributors and several worldwide, including Asia, the Middle East, Oceania, Europe, and Africa. It is ISO 9001 and ISO 9002 certified, while the Kyoto South brand and Tesque factory are ISO 14001 certified.
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Alfa Aesar, Thermo Fisher Scientific.
J62432 Bacitracin
Company Overview
Alfa Aesar is based in Lancashire, United Kingdom. Alfa Aesar is part of Thermo Fisher Scientific, is a manufacturer and supplier of chemicals, metals, and life science products for research and development. Alfa Aesar’s product lines include chemicals, life science, materials & metals, catalysts, and analytical & lab ware. Chemical offerings include inorganic compounds, organic compounds, organometallic, and solvents. Life sciences include biotechnology products, cellular & molecular biology, genomics, and immunology. Materials & metal include alloys, carbon, etchants, and more. Catalysts include ferrocenes, fuel cell products, and precious metals & catalysts. Alfa Aesar also offers custom manufacturing options.
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Jigs chemical
Bacitracin
Company Overview
Jigs Chemical was established in 1998 and is based in India with global offices in the USA, UK, Canada, and Australia. Jigs Chemical is a manufacturer, distributor, and marketing & sales provider for organizations in India, specializing in chemicals and active pharmaceutical ingredients for pharmaceutical, agriculture, ceramics, metal treatment, and other industries. Jigs Chemical helps facilitate international customers to obtain chemicals from India, providing import and export assistance. Jigs Chemical’s product catalog includes over 40000 active pharmaceutical ingredients, commonly called APIs, their respective intermediates, and other chemicals.
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Otto Chemie Pvt. Ltd
Bacitracin
Distributor Overview
Founded in Mumbai, India in 2006, Otto Chemie Pvt. Ltd. is an ISO 9001:2015 & GMP certified chemical manufacturing company and distributor. Otto Chemie serves customers in many industries including agriculture and food processing, pharmaceuticals, oil & gas, cement, as well as educational and R&D industries. Product offerings include antibiotics, amino acids, vitamins, detergents, ionic liquids, materials science compounds, labware, oil, metal & ceramic science compounds and tools, oils, reagents, solvents.
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Xellia Pharmaceuticals ApS
Bacitracin
Distributor Overview
Xellia Pharmaceuticals, founded in 1903 and headquartered in Copenhagen, Denmark, serves as a supplier of anti-infective drugs, encompassing active pharmaceutical ingredients and injectable products to combat serious and life-threatening infections. The company specializes in developing pharmaceutical ingredients for treating bacterial and fungal infections, including antibiotic-resistant strains. Since 2013, it has been wholly acquired by Novo Holdings A/S. With a global presence, Xellia operates four state-of-the-art manufacturing facilities in Denmark, Hungary, China, and the United States.
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NATIONAL ANALYTICAL CORPORATION
BACITRACIN
Distributor Overview
National Analytical Corporation (NAC) is located in Mumbai, India. NAC was founded in 2009 as a distributor of laboratory grade chemicals used in numerous industries. NAC’s chemical offerings include biochemical & reagents such s Prunetin and 1,2-dipalmitoly-rac-glycerol, analytical grade chemicals such as chicoric acid and Vitamin E solutions, laboratory chemicals such as formic acid and nitric acid, gas chromatography chemicals such as Aalborg mass flowmeter battery kits and DEX 225, reference standard chemicals such as Palladium in HNO3, oral solid dosage forms, such as cellulosic and protect film coating systems, parenteral dosage forms, beverage & nutrition, and coating chemicals.
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Bacitracin Manufacturer Ranking
*Including some distributors, etc.Ranking as of April 2024
Derivation Method| Rank | Company | Click Share |
|---|---|---|
| 1 | MedChemExpress |
22.0%
|
| 2 | MilliporeSigma |
22.0%
|
| 3 | Merck |
19.5%
|
| 4 | KANTO CHEMICAL CO.,INC. |
12.2%
|
| 5 | Otto Chemie Pvt. Ltd |
7.3%
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| 6 | Santa Cruz Biotechnology, Inc. |
7.3%
|
| 7 | Alfa Aesar, Thermo Fisher Scientific. |
4.9%
|
| 8 | Jigs chemical |
2.4%
|
| 9 | NATIONAL ANALYTICAL CORPORATION |
2.4%
|
Derivation Method
The ranking is calculated based on the click share within the bacitracin page as of April 2024. Click share is defined as the total number of clicks for all companies during the period divided by the number of clicks for each company.Number of Employees
- KANTO CHEMICAL CO.,INC.: 1,062
- NATIONAL ANALYTICAL CORPORATION: 10
Newly Established Company
- NATIONAL ANALYTICAL CORPORATION: 2009 (15 years ago)
- Jigs chemical: 1998 (26 years ago)
- KANTO CHEMICAL CO.,INC.: 1944 (80 years ago)
Company with a History
- nacalai: 1934 (90 years ago)
- KANTO CHEMICAL CO.,INC.: 1944 (80 years ago)
- Jigs chemical: 1998 (26 years ago)
Bacitracin Manufacturers in United States
*Including some distributors, etc.
Global Distribution of Bacitracin Manufacturers by Country
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
United States of America
|
2 | 25.0% |
Japan
|
2 | 25.0% |
India
|
2 | 25.0% |
United Kingdom
|
1 | 12.5% |
Denmark
|
1 | 12.5% |
